UNDERSTAND MY HEALTH

Immune & Inflammatory Health After 60

What Part of My Health Am I Improving?

Immune & Inflammatory Health is your defence, repair and regulation system. Explore immune function, chronic low-grade inflammation, recovery and the lifestyle factors associated with healthier inflammatory regulation as we age.

Why This Matters After 60

Healthy ageing is not about one number, one exercise or one food. This hub brings together the explanations, practical actions and evidence connected with Immune & Inflammatory Health.

Understand → Improve → Measure

Use the resources below to understand the topic, connect it with the relevant parts of the OVER 60s QoL Guys system and identify useful next steps. Measurement should support better decisions — not simply collect numbers.

Explore Immune & Inflammatory Health

THE BIG PICTURE

Understanding Immune & Inflammatory Health After 60

The immune system protects against infection, helps coordinate repair and continually distinguishes threats from the body's own tissues. Inflammation is part of that defence-and-repair system; it is not inherently harmful. Problems arise when immune responses are insufficient, misdirected or remain dysregulated.

Ageing is associated with changes in immune function and, in many people, chronic low-grade sterile inflammation often described in research as 'inflammaging'. This is an important field of ageing biology, but it does not mean that all inflammation is bad or that a consumer product can simply 'switch inflammation off'.

Acute vs Chronic Inflammation

Short-term inflammation is an essential response to injury and infection. Chronic low-grade inflammation is different and is associated with ageing and several age-related conditions. Cause, consequence and context need to be distinguished carefully.

Immune Ageing Is Complex

Immune ageing involves changes across multiple cell types, signalling systems and tissues. Infection risk, vaccine responses, chronic disease, medications, nutrition and other factors can interact, so 'immune health' cannot be reduced to one food, supplement or blood marker.

What Can You Work On?

Regular physical activity, adequate nutrition, sleep, avoiding smoking and appropriate vaccination and medical care are practical parts of maintaining health as we age. The goal is healthy immune regulation and resilience — not indiscriminately 'boosting' the immune system.

What Should You Measure?

There is no single consumer score that captures immune and inflammatory health. Clinical inflammatory markers have specific uses and limitations and should be interpreted in context. Recurrent infections, persistent unexplained symptoms or abnormal laboratory results warrant professional assessment.

Language matters: The OVER 60s QoL Guys will use terms such as 'support healthy immune function' and 'associated with healthier inflammatory regulation' rather than unsupported claims to 'boost immunity' or 'eliminate inflammation'.

NU-AGE: Mediterranean Diet, Gut Microbiome and Healthy Ageing

Dietary Intervention and Microbiome Analysis • 2020 • Ghosh and colleagues; GutResearch SummaryNU-AGE investigated whether a Mediterranean-style dietary intervention could alter the gut microbiome in older people. Researchers examined 612 non-frail or pre-frail...

Gut-Microbiota-Targeted Diets Modulate Human Immune Status

Small Randomised Dietary Trial • 2021 • Wastyk and colleagues; CellResearch SummaryThis study compared diets rich in fermented foods or plant fibre and examined changes in gut microbes and immune measures. The 17-week investigation included 18 participants in each...

Hallmarks of Aging: An Expanding Universe

Scientific Review • 2023 • López-Otín and colleagues; CellResearch SummaryThis review organises the biology of ageing into interacting processes that help explain why cells and tissues gradually lose resilience. The expanded framework includes changes involving...

Health Topics A–Z

Website • US National Institute on AgingResearch SummaryThe National Institute on Aging provides a broad collection of health information designed for older adults and the people who support them. The official site describes its material as informed by research and...

Turn Knowledge Into Action

The Whole Body Health Assessment helps you look across health, capability and daily behaviour so you can identify strengths, gaps and priorities.

Start the Whole Body Health Assessment

Educational information only. The assessment and website do not diagnose disease or replace individual medical care.